Clayton is a city in and the county seat of St. Louis County, Missouri, United States, and borders the city of St. Louis. The population was 15,939 at the 2010 census. The city was organized in 1877 and is named after Ralph Clayton, who donated the land for the courthouse. The city is also known for its multiple skyscrapers in its business district.
The architecture of central Clayton reflects its economic activity and eras of growth. An impressive collection of mid-century Modernist low and high rise structures contrast with earlier mansions, stores and flats.
In the St. Louis region, Clayton is well known for housing a wealthy and educated young professional, often dual-income population.
Armstrong Teasdale, Brown Shoe Company (owner of Famous Footwear and Shoes.com), Centene, Enterprise Rent-a-Car, Cassidy Turley, Olin, and Straub's Markets are headquartered in Clayton.